Fig. 1. Increased ZNF281 expression in CRC. (A) Analysis of ZNF281 expression in normal colon tissues (N=50) and CRC tissues (N=383) in the TCGA cohort. (B) Analysis of ZNF281 expression in paired normal colon and CRC tissues (N=32) in the TCGA cohort. (C) ZNF281 mRNA expression levels in paired normal colon and tumor tissues (N=30) from the Huai He cohort. (D) ZNF281 expression was measured in the CRC tissues and respective adjacent nontumor tissues in 8 typical patients. Mean ± SEM, t-test, *P<0.05, **P<0.01, ***P<0.001.